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PUBLICATIONS
  YEAR REFERENCE DOWNLOAD RELATED LINKS
2008 Lan Hu, Daniel Segrè and Temple F. Smith, Evolutionary changes in gene regulation from a comparative analysis of multiple drosophila species, Genome Informatics (2007), 18, 12-22.    
2007 Matthew A. Wright, Peter Kharchenko, George M. Church and Daniel Segrè, Chromosomal periodicity of evolutionarily conserved gene pairs, Proc. Natl. Acad. Sci. USA (2007), 104 (25), 10559-10564. [PDF] [PNAS online] [Supp. Info] [MSB blog]
2006 Jason Raymond and Daniel Segrè, The effect of oxygen on biochemical networks and the evolution of complex life, Science (2006), 311, 1764-1767. [PDF] [Science] [Perspective] [Interactive Network] [The Scientist] [Seed] [La Stampa]
2005 Daniel Segrè, Alexander DeLuna, George M. Church and Roy Kishony, Modular epistasis in yeast metabolism, Nature Genetics (2005), 37(1), 77-83. [PDF] [Nature Genetics] [Data and Algorithms]
2005 Daniel Segrè, Life as a cellular automaton, Journal of Biogeography (2005) 32, 1681. (Review of the The Principles of Life by Tibor Ganti) [PDF]  
2005 Daniel Segrè, Ventimila geni sotto i mari dei tropici, Darwin (2005) May-June, 56-61. (Review, in Italian) [PDF]  [Links]
2004 Daniel Segrè, The regulatory software of cellular metabolism, Trends in Biotechnology (2004), 22 (6), 261-265. (Commentary of Ihmels et al. Nat. Biotech. 2003) [PDF]  
2004 Daniel Segrè and Doron Lancet, Theoretical and computational approaches to the study of the origins of life, in Origins: Genesis, Evolution and Diversity of Life (2004), COLE series, Vol.6, Kluwer, J. Seckbach (ed.)   [Amazon]
2003 Daniel Segrè, Jeremy Zucker, Jeremy Katz, Xiaoxia Lin, Patrik D'haeseleer, Wayne P. Rindone, Peter Kharchenko, Dat Nguyen, Matthew A. Wright and George M. Church, From annotated genomes to metabolic flux models and kinetic parameter fitting, Omics (2003), 7(3), 301-316. [PDF] [Biospice]
2002 Daniel Segrè, Dennis Vitkup and George Church, Analysis of optimality in natural and perturbed metabolic networks, Proc. Natl. Acad. Sci. USA (2002), 99(23), 15112-15117. [PDF] [PNAS on line] [Supplementary Material]
2003 Barak Shenhav, Daniel Segrè and Doron Lancet, Mesobiotic emergence: molecular and ensemble complexity in early evolution, Advances in Complex Systems (2003), 6 (1), 15-35.
 
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2001 Daniel Segrè, Barak Shenhav, Ron Kafri and Doron Lancet, The molecular roots of compositional inheritance, Journal of Theoretical Biology (2001), 213, 481-491.
 
[PDF]  
2001 Daniel Segrè, Dafna Ben-Eli, David Deamer and Doron Lancet, The Lipid World, Origins Life Evol. Biosphere (2001) 31, 119-145.
 
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2000 Yoav Gilad, Daniel Segrè, Karl Skorecki, Michael W. Nachman, Doron Lancet and Dror Sharon, Dichotomy of single-nucleotide polymorphism haplotypes in olfactory receptor genes and pseudogenes, Nature Genetics (2000) 26, 221-224. [PDF]  
2000 Daniel Segrè, Dafna Ben-Eli and Doron Lancet, Compositional genomes: prebiotic information transfer in mutually catalytic noncovalent assemblies, Proc. Natl. Acad. Sci. USA (2000), 97(8), 4112-4117. [PNAS on line] [PDF] [Software & extras]
EMBO
   Reports Cover 2000 Daniel Segrè and Doron Lancet, Composing Life, EMBO Reports (2000), 1(3), 217-222. [PDF] [cover]
1999 Daniel Segrè and Doron Lancet, A statistical chemistry approach to the origin of life, Chemtracts - Biochemistry and Molecular Biology (1999) 12 (6), 382-397. [preprint PDF]  
  2000 Daniel Segrè, Dafna Ben-Eli and Doron Lancet, Prebiotic evolution of amphiphilic assemblies far from equilibrium: from compositional information to sequence-based biopolymers, Astronomical Society of the Pacific Conference Series Vol.213, Sheridan Books, Michigan, 2000, 373-378 [preprint PDF]  
1998 Daniel Segrè , Doron Lancet, Ora Kedem and Yitzhak Pilpel, Graded Autocatalysis Replication Domain (GARD): kinetic analysis of self-replication in mutually catalytic sets, Origins Life Evol. Biosphere (1998) Vol.28, 501-514.
 
[PDF] [Medline abstract]  
  1998 Daniel Segrè, Yitzhak Pilpel and Doron Lancet, Mutual catalysis in sets of prebiotic organic molecules: Evolution through computer simulated chemical kinetics, Physica A (1998) 249, 558-564.
 
[PDF]  
  1999 Daniel Segrè, Dafna Ben-Eli, Yitzhak Pilpel, Ora Kedem and Doron Lancet, GARDobes: Primordial cell nano-precursors with organic catalysis, compositional genome and capacity to evolve, In Instruments, Methods, and Missions for Astrobiology II, Richard B. Hoover, Ed., Proceedings of SPIE, Vol.3755, 144-162 (1999) [PDF(5M)]  
  1998 Daniel Segrè and Doron Lancet, Mutually catalytic amphiphiles: simulated chemical evolution and implications to exobiology, J.Chela-Flores and F.Raulin (eds), Exobiology: Matter, Energy and Information in the Origin and Evolution of Life in the Universe, 123-131, Kluwer Academic Publishers, The Netherlands, 1998. [preprint PDF]  
  1997 Daniel Segrè, Yitzhak Pilpel, Gustavo Glusman and Doron Lancet, Self-replication and evolution in primordial mutually catalytic set, in C. B. Cosmovici, S. Bowyer, D. Werthimer, Astronomical and Biochemical Origins and the Search for Life in the Universe, Editrice Compositori, Bologna, 1997, 469-476